Laboratory of Bioinorganic Immunology & Drug Discovery
We are a dynamic and multinational team working in the Institute of Pharmaceutical Sciences at King's College London
Research
Our multidisciplinary research crosses the boundaries of bioinorganic chemistry and immunology/virology. We use a combination of molecular biology and cell biological methods, biophysical techniques, biochemical assays, and computational biochemistry.
The research in our group is broadly divided into two themes: (i) Protein engineering to design and develop new therapeutics and (ii) Elucidating the function of iron-sulfur clusters, one of the oldest bioinorganic cofactors of life, at the crossroads of the immune response and cancer.
News & Events
Latest Publications
Latest Publications
Ancient complexes of iron and sulfur modulate oncogenes and oncometabolism
Inorganic complexes of iron and sulfur, that is, iron-sulfur [FeS] clusters, have played a fundamental role in life on Earth since the prebiotic period. We discuss how three [FeS] proteins involved in the innate immune response play a role in oncogene expression/function and oncometabolism.
