Our Laboratory
Our laboratory joined the Institute of Pharmaceutical Science at King's College London in 2021. We are located at the Franklin-Wilkins Building in the heart of London.
The laboratory has all the facilities for cloning, expression, and purification of a wide range of proteins. The lab is equipped with an anaerobic glovebox to work with oxygen-sensitive iron-sulfur proteins, a state-of-the-art system for running western blots, and a dedicated LC-MS system to study enzyme reactions. We have access to state-of-the-art research facilities including a fully equipped cell culture lab, modern protein and western blot imaging system, UV-visible spectrophotometers, and NMR facility.
Our laboratory leads a European Cooperation in Science and Technology (COST) Action crossing boundaries of bioinorganic chemistry and immunology (read more). We collaborate with various groups in the United Kingdom and across Europe.
The Team
Our team is dynamic and multicultural. We are driven by our passion and desire to reveal the secrets of life and use the knowledge to treat diseases like cancer.
Kourosh H. Ebrahimi
Principle Investigator
I was born in Iran. After finishing my undergraduate and graduate studies in Chemical and Biochemical Engineering, respectively, I did my PhD in Bioinorganic Chemistry under the supervision of Prof Wilfred R. Hagen (TU Delft). As a postdoc, I had the privilege to work with Prof Michael Farzan (Harvard Medical School), and Prof Fraser A. Armstrong, Prof William S. James, and Prof James McCullagh (all at the University of Oxford). In October 2021, I joined the Institute of Pharmaceutical Science as a Lecturer. Painting with oil on canvas is my hobby.
Yujie Sheng
PhD Student
I am from China. I got my master's degree in Drug Discovery and Development (UCL). My research interest lies in the interface of immunology and drug discovery. In my PhD studies, I will engineer ferritin nanocages to develop new immunotherapies. Cycling and listening to music are my hobbies.
Thao Nghi Hoang
PhD Student, Vietnam Ministry of Education Fellow
I come from Vietnam. I have an MSc degree in Pharmaceutical Sciences. My research elucidates the emerging role of iron-sulfur clusters and proteins like the antiviral enzyme SAND in immunometabolism and oncometabolism. I am a movieholic and also have a crazy passion for food.
Maike Henschel
PhD candidate, MRC DTP rotation
Co-supervised by Dr Shahram Kordasti (Comprehensive Cancer Center)
I am from Germany. I hold a BSc degree in Biochemistry and Cell Biology from Constructor University (formerly, Jacobs University). My research interests lie in understanding the mechanistic roles of proteins regulating T-cell function and cancer growth. Outside the lab, I enjoy doing jigsaw puzzles, watching good movies, and reading.
Pei-Hsi Tai (Peggy)
M.Sc. Student
I am from Taiwan. I hold a BSc degree in Chemistry from National Taiwan Normal University. My research interests are in protein biochemistry and bioinorganic chemistry. Outside of study, I like basketball and music.
Zheng Chen
M.Sc. Student
I am from China. I hold a BSc degree in Biotechnology from University of Science and Technology Beijing. My research interest lies in investigating the activation mechanism of radical-SAM enzymes. Playing billiards and reading novels are my hobbies.
Yingxin Liu
M.Sc. Student
I come from China. I hold a Bachelor's degree in Biological Sciences from South China Agricultural University. My current research project is related developing ferritin-based nanomedicine. In addition to my studies, I enjoy photography and fitness.